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which is the best prediction

Suppose that 4.5% of the people in the world have a particular genetic defect and that a screening test is 81% accurate for people who have it and 88% accurate for people who do not.
If 1300 people are screened for the defect, which is the best prediction for the number of people with the defect who are identified as not having it?
A: 11
B: 16
C; 48
D: 59

 
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