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T.T. presents to rheumatology clinic on referral from her primary-care provider. She is 9 years old.

T.T. presents to rheumatology clinic on referral from her primary-care provider. She is 9 years old and has been complaining at home of her shoes hurting her feet and not being able to run with her classmates at school. On physical examination it is noted she has multiple swollen, erythematous joints (tarsometatarsal and metatarsocuneiform joints bilaterally on the feet, ankles bilaterally, knees bilaterally). Her CBC values are all normal, her ESR is normal, and her RF is positive. In addition to NSAID and steroid therapy, the rheumatologist would like to start a DMARD agent. What DMARD options are available to treat T.T.’s JIA?

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